Small polypoid lesions of the gallbladder. Differential diagnosis and surgical indications by helical computed tomography

Hiroyoshi Furukawa, Tomoo Kosuge, Kazuaki Shimada, Junji Yamamoto, Yae Kanai, Kiyoshi Mukai, Ryoko Iwata, Kyosuke Ushio

研究成果: Article

61 引用 (Scopus)

抄録

Objectives: To demonstrate the helical computed tomographic (CT) features of small polypoid lesions of the gallbladder and to establish a clinical strategy based on CT findings for the treatment of such lesions. Design: Validation cohort study. Setting: Tertiary care public hospital. Patients: Thirty-one patients with polypoid lesions of the gallbladder (≤3 cm) underwent CT followed by resection. Main Outcome Measure: The detectability of the lesions on both unenhanced and enhanced CT and the configuration of the lesions on enhanced CT were prospectively evaluated in comparison with the histopathological findings. Results: Unenhanced CT detected 14 (45%) of the 31 lesions, whereas enhanced CT detected all of the lesions. The detection rates of the neoplastic lesions (adenoma, adenocarcinoma, and metastatic tumor) and cholesterol polyps were 81% (13/16) and 7% (1/15), respectively (P<.001). Among the 20 lesions demonstrated as pedunculated, 6 (30%) were neoplastic, whereas 10 (91%) of the 11 lesions demonstrated as sessile were neoplastic (P<.001). When a lesion was demonstrated on unenhanced CT or its shape was sessile on enhanced CT, the case was diagnosed as a neoplastic lesion. The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the CT diagnosis of the neoplastic lesions were 88% (14/16), 87% (13/15), 88% (14/16), 87% (13/15), and 87% (27/31), respectively. Conclusion: Computed tomography can differentiate neoplastic and nonneoplastic small polypoid lesions of the gallbladder and reliably identify the presence of neoplastic lesions that should be resected.

元の言語English
ページ(範囲)735-739
ページ数5
ジャーナルArchives of Surgery
133
発行部数7
DOI
出版物ステータスPublished - 1998 7
外部発表Yes

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Spiral Computed Tomography
Gallbladder
Differential Diagnosis
Validation Studies
Public Hospitals
Tertiary Healthcare
Polyps
Adenocarcinoma
Cohort Studies
Cholesterol
Tomography
Outcome Assessment (Health Care)
Sensitivity and Specificity
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Surgery

これを引用

Small polypoid lesions of the gallbladder. Differential diagnosis and surgical indications by helical computed tomography. / Furukawa, Hiroyoshi; Kosuge, Tomoo; Shimada, Kazuaki; Yamamoto, Junji; Kanai, Yae; Mukai, Kiyoshi; Iwata, Ryoko; Ushio, Kyosuke.

:: Archives of Surgery, 巻 133, 番号 7, 07.1998, p. 735-739.

研究成果: Article

Furukawa, Hiroyoshi ; Kosuge, Tomoo ; Shimada, Kazuaki ; Yamamoto, Junji ; Kanai, Yae ; Mukai, Kiyoshi ; Iwata, Ryoko ; Ushio, Kyosuke. / Small polypoid lesions of the gallbladder. Differential diagnosis and surgical indications by helical computed tomography. :: Archives of Surgery. 1998 ; 巻 133, 番号 7. pp. 735-739.
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abstract = "Objectives: To demonstrate the helical computed tomographic (CT) features of small polypoid lesions of the gallbladder and to establish a clinical strategy based on CT findings for the treatment of such lesions. Design: Validation cohort study. Setting: Tertiary care public hospital. Patients: Thirty-one patients with polypoid lesions of the gallbladder (≤3 cm) underwent CT followed by resection. Main Outcome Measure: The detectability of the lesions on both unenhanced and enhanced CT and the configuration of the lesions on enhanced CT were prospectively evaluated in comparison with the histopathological findings. Results: Unenhanced CT detected 14 (45{\%}) of the 31 lesions, whereas enhanced CT detected all of the lesions. The detection rates of the neoplastic lesions (adenoma, adenocarcinoma, and metastatic tumor) and cholesterol polyps were 81{\%} (13/16) and 7{\%} (1/15), respectively (P<.001). Among the 20 lesions demonstrated as pedunculated, 6 (30{\%}) were neoplastic, whereas 10 (91{\%}) of the 11 lesions demonstrated as sessile were neoplastic (P<.001). When a lesion was demonstrated on unenhanced CT or its shape was sessile on enhanced CT, the case was diagnosed as a neoplastic lesion. The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the CT diagnosis of the neoplastic lesions were 88{\%} (14/16), 87{\%} (13/15), 88{\%} (14/16), 87{\%} (13/15), and 87{\%} (27/31), respectively. Conclusion: Computed tomography can differentiate neoplastic and nonneoplastic small polypoid lesions of the gallbladder and reliably identify the presence of neoplastic lesions that should be resected.",
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AU - Shimada, Kazuaki

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AU - Kanai, Yae

AU - Mukai, Kiyoshi

AU - Iwata, Ryoko

AU - Ushio, Kyosuke

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N2 - Objectives: To demonstrate the helical computed tomographic (CT) features of small polypoid lesions of the gallbladder and to establish a clinical strategy based on CT findings for the treatment of such lesions. Design: Validation cohort study. Setting: Tertiary care public hospital. Patients: Thirty-one patients with polypoid lesions of the gallbladder (≤3 cm) underwent CT followed by resection. Main Outcome Measure: The detectability of the lesions on both unenhanced and enhanced CT and the configuration of the lesions on enhanced CT were prospectively evaluated in comparison with the histopathological findings. Results: Unenhanced CT detected 14 (45%) of the 31 lesions, whereas enhanced CT detected all of the lesions. The detection rates of the neoplastic lesions (adenoma, adenocarcinoma, and metastatic tumor) and cholesterol polyps were 81% (13/16) and 7% (1/15), respectively (P<.001). Among the 20 lesions demonstrated as pedunculated, 6 (30%) were neoplastic, whereas 10 (91%) of the 11 lesions demonstrated as sessile were neoplastic (P<.001). When a lesion was demonstrated on unenhanced CT or its shape was sessile on enhanced CT, the case was diagnosed as a neoplastic lesion. The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the CT diagnosis of the neoplastic lesions were 88% (14/16), 87% (13/15), 88% (14/16), 87% (13/15), and 87% (27/31), respectively. Conclusion: Computed tomography can differentiate neoplastic and nonneoplastic small polypoid lesions of the gallbladder and reliably identify the presence of neoplastic lesions that should be resected.

AB - Objectives: To demonstrate the helical computed tomographic (CT) features of small polypoid lesions of the gallbladder and to establish a clinical strategy based on CT findings for the treatment of such lesions. Design: Validation cohort study. Setting: Tertiary care public hospital. Patients: Thirty-one patients with polypoid lesions of the gallbladder (≤3 cm) underwent CT followed by resection. Main Outcome Measure: The detectability of the lesions on both unenhanced and enhanced CT and the configuration of the lesions on enhanced CT were prospectively evaluated in comparison with the histopathological findings. Results: Unenhanced CT detected 14 (45%) of the 31 lesions, whereas enhanced CT detected all of the lesions. The detection rates of the neoplastic lesions (adenoma, adenocarcinoma, and metastatic tumor) and cholesterol polyps were 81% (13/16) and 7% (1/15), respectively (P<.001). Among the 20 lesions demonstrated as pedunculated, 6 (30%) were neoplastic, whereas 10 (91%) of the 11 lesions demonstrated as sessile were neoplastic (P<.001). When a lesion was demonstrated on unenhanced CT or its shape was sessile on enhanced CT, the case was diagnosed as a neoplastic lesion. The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the CT diagnosis of the neoplastic lesions were 88% (14/16), 87% (13/15), 88% (14/16), 87% (13/15), and 87% (27/31), respectively. Conclusion: Computed tomography can differentiate neoplastic and nonneoplastic small polypoid lesions of the gallbladder and reliably identify the presence of neoplastic lesions that should be resected.

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