Sneddon's syndrome

Sneddon's syndrome is a rare non-inflammatory arteriopathy labeled as a neurodermatologic disorder and defined by multiple cerebrovascular accidents and extensive livedo racemosa. It is a slowly progressive condition, and often unrecognized. The condition has a slow progress starting with non - specific symptoms, then livedo racemosa, and later, neurological involvement Autoimmune process against the endothelial cell has been observed, particularly occurring in combination with the Hughes antiphospholipid antibody syndrome The diagnosis of Sneddon's syndrome needs extensive laboratory evaluation. There is no specific investigation in Sneddon's syndrome, and the only diagnostic criterion is the histological exam of skin biopsy. There is no specific treatment for Sneddon's syndrome, only the symptomatic and supportive measures.