Split Genes

K. Fujishima, Akio Kanai

研究成果: Chapter

抄録

Genomic and transcriptomic analyses have revealed an unexpected complexity of genes in diverse living organisms. In eukaryotes, most protein-coding genes are interrupted by intronic sequences, which split the genes into multiple exons. Most of these genes undergo a process called 'alternative splicing', in which cis-encoded exons are joined in different combinations to produce various messenger RNAs (mRNAs). Some eukaryotic mRNAs and archaeal tRNAs are produced by the trans-splicing of multiple transcripts expressed from distinct genes. In this article, we introduce the different modes of gene splitting found in the Eukaryotes and the Archaea and discuss their possible roles in biological systems.

本文言語English
ホスト出版物のタイトルBrenner's Encyclopedia of Genetics
ホスト出版物のサブタイトルSecond Edition
出版社Elsevier Inc.
ページ543-544
ページ数2
ISBN(電子版)9780080961569
ISBN(印刷版)9780123749840
DOI
出版ステータスPublished - 2013 2 27

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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