Statistical study on the self-selection bias in FDG-PET cancer screening by a questionnaire survey

A questionnaire survey was performed to investigate the possible presence of self-selection bias in ¹⁸F-FDG PET cancer screening (PET cancer screening). Respondera to the questionnaires survey consisted of 80 healthy persons, who answered whether they undergo PET cancer screening, health consciousness, age, sex, and smoking history. The univariate and multivariate analyses on the four parameters were performed between the responders who were to undergo PET cancer screening and the responders who were not. Statistically significant difference was found in health consciousness between the above-mentioned two groups by both univariate and multivariate analysis with the odds ratio of 2.088. The study indicated that self-selection bias should exist in PET cancer screening.