Stem cell therapy for ischemic stroke using iPS cells

Koichi Oki

研究成果: Article査読

抄録

Recently, several stem cell-based approaches have been considered as a novel treatment for stroke, such as delivery of non neural stem cells, stimulation of endogenous neural stem cells, and transplantation of neural stem cells. Among them, transplantation of neural stem cells is thought to have an advantage for functional recovery through neuronal replacement rather than other mechanisms. We demonstrated that human iPS cells derived neural stem cells form functional neurons and improve recovery after grafting in stroke-damaged rodents without tumor formation. Here we discuss about the potential and clinical application of iPS cells for stroke therapy.

本文言語English
ページ(範囲)1017-1019
ページ数3
ジャーナルClinical Neurology
53
11
DOI
出版ステータスPublished - 2013 12 1

ASJC Scopus subject areas

  • 臨床神経学

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