Stereochemistry of Hydrogen Addition to C-25 of Desmosterol by Sterol-Δ24-Reductase of Rat Liver Homogenate

Tomoko Yagi, Noriko Kobayashi, Masuo Morisaki, Noriyuki Hara, Yoshinori Fujimoto

研究成果: Article査読

8 被引用数 (Scopus)

抄録

Chemically synthesized (26)- and (27)-methyl-13C-labeled desmosterol (3, 5) were separately incubated with rat liver homogenate. 13C-NMR analysis of the incubation products indicated that the C-25 hydrogen of cholesterol was introduced from the si-face of 3 and the re-face of 5.

本文言語English
ページ(範囲)680-682
ページ数3
ジャーナルChemical and Pharmaceutical Bulletin
42
3
DOI
出版ステータスPublished - 1994

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

フィンガープリント 「Stereochemistry of Hydrogen Addition to C-25 of Desmosterol by Sterol-Δ<sup>24</sup>-Reductase of Rat Liver Homogenate」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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