Stereoselective synthesis of 1,2-cis galactosides: synthesis of a glycolipid containing Galα1-6Gal component from Zygomycetes species

Noriyasu Hada; Junko Oka; Ayaka Nishiyama; Tadahiro Takeda

doi:10.1016/j.tetlet.2006.06.181

Stereoselective synthesis of 1,2-cis galactosides: synthesis of a glycolipid containing Galα1-6Gal component from Zygomycetes species

Noriyasu Hada, Junko Oka, Ayaka Nishiyama, Tadahiro Takeda

薬学科

研究成果: Article › 査読

17 被引用数 (Scopus)

抄録

An α-selective galactosylation was demonstrated under various conditions. Among these α-galactoside approaches, high α-selectivity was achieved by the virtue of 4,6-O-di-tert-butylsilylene (DTBS) group. Yield was further improved by the influence of a 2-O-benzylated donor compared to 2-O-benzoylated donor. This method was then applied to the first highly stereoselective synthesis of a newly found trisaccharide glycosphingolipid in Zygomycetes species.

本文言語	English
ページ（範囲）	6647-6650
ページ数	4
ジャーナル	Tetrahedron Letters
巻	47
号	37
DOI	https://doi.org/10.1016/j.tetlet.2006.06.181
出版ステータス	Published - 2006 9 11

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

文献へのアクセス

10.1016/j.tetlet.2006.06.181

フィンガープリント「Stereoselective synthesis of 1,2-cis galactosides: synthesis of a glycolipid containing Galα1-6Gal component from Zygomycetes species」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

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abstract = "An α-selective galactosylation was demonstrated under various conditions. Among these α-galactoside approaches, high α-selectivity was achieved by the virtue of 4,6-O-di-tert-butylsilylene (DTBS) group. Yield was further improved by the influence of a 2-O-benzylated donor compared to 2-O-benzoylated donor. This method was then applied to the first highly stereoselective synthesis of a newly found trisaccharide glycosphingolipid in Zygomycetes species.",

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author = "Noriyasu Hada and Junko Oka and Ayaka Nishiyama and Tadahiro Takeda",

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T1 - Stereoselective synthesis of 1,2-cis galactosides

T2 - synthesis of a glycolipid containing Galα1-6Gal component from Zygomycetes species

AU - Hada, Noriyasu

AU - Oka, Junko

AU - Nishiyama, Ayaka

AU - Takeda, Tadahiro

PY - 2006/9/11

Y1 - 2006/9/11

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KW - 1,2-cis-Glycoside

KW - Di-tert-butylsilylene group

KW - Zygomycetes species

KW - d-Galactose

KW - α-Galactosylation

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