Stereoselective synthesis of (E)- and (Z)-3-hydroxy-2-methyl-1-alkenyl iodides by base-promoted ring-opening of iodomethylated epoxides

Takahiro Ichige, Daisuke Matsuda, Masaya Nakata

研究成果: Article

5 引用 (Scopus)

抜粋

Both (E)- and (Z)-3-hydroxy-2-methyl-1-alkenyl iodides were stereoselectively synthesized from iodomethylated epoxides by treatment with sodium hexamethyldisilazane in DMF and with LDA in THF (or lithium 2,2,6,6-tetramethylpiperidide in THF), respectively.

元の言語English
ページ(範囲)4843-4848
ページ数6
ジャーナルTetrahedron Letters
47
発行部数28
DOI
出版物ステータスPublished - 2006 7 12

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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