Structure of arnebinol, a new ANSA-type monoterpenylbenzenoid with inhibitory effect to prostaglandin biosynthesis

Yao Xin-Sheng, Yutaka Ebizuka, Hiroshi Noguchi, Fumiyuki Kiuchi, Yoichi Iitaka, Ushio Sankawa, Haruo Seto

研究成果: Article

39 引用 (Scopus)

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The two inhibitors of prostaglandin biosynthesis were isolated from the root of Arnebia euchroma (Boraginaceae). A colourless crystalline compound was identified to be a polyketide, des-0-methyllasiodiplodin (3) formerly obtained from a fungus, Lasiodiplodia theobromae. The structure of the other colourless crystalline compound, named arnebinol (1), was deduced from spectral investigations to be a dehydroderivative of geranylhydroquinone and finally determined by X-ray analysis to be a novel ansa-type monoterpenylbenzenoid.

元の言語English
ページ(範囲)2407-2410
ページ数4
ジャーナルTetrahedron Letters
24
発行部数23
DOI
出版物ステータスPublished - 1983
外部発表Yes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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