Studies on Crude Drugs Effective on Visceral Larva Migrans. I. Identification of Larvicidal Principles in Betel Nuts

Fumiyuki Kiuchi, Naoshi Miyashita, Yoshisuke Tsuda, Hiroyuki Yoshimura, Kaoru Kondo

研究成果: Article

67 引用 (Scopus)

抜粋

Larvicidal principles obtained from the 50% aqueous acetone extract of betel nuts (Areca catechu) were revealed to be a mixture of fatty acids. They were identified by GC-MS analysis as lauric, myristic, palmitic, and oleic acids. Determination of the larvicidal activities of fatty acids and aliphatic alcohols with various alkyl chain lengths, and of analogous compounds with various functional groups, suggested that the balance between hydrophilicity and hydrophobicity is important for the larvicidal activity.

元の言語English
ページ(範囲)2880-2886
ページ数7
ジャーナルChemical and Pharmaceutical Bulletin
35
発行部数7
DOI
出版物ステータスPublished - 1987

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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