抄録
The basic structure of the C(15)-C(27) part of irumamycin (1) was synthesized. Stereoselective assembly of C16, 17, 22, and an extra C21 stereocenter was achieved by two-directional Brown's asymmetric allyl boration. Group selective PMP acetal formation and oxidative cleavage of vinyl group facilitated the differentiation of the ends of a two-directionally synthesized chain.
本文言語 | English |
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ページ(範囲) | 413-416 |
ページ数 | 4 |
ジャーナル | Tetrahedron Letters |
巻 | 48 |
号 | 3 |
DOI | |
出版ステータス | Published - 2007 1 15 |
外部発表 | はい |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry