Successful resolution of a left ventricular thrombus with apixaban treatment following acute myocardial infarction

Yoshinori Mano, Kimi Koide, Hiroaki Sukegawa, Masaki Kodaira, Takahiro Ohki

研究成果: Article査読

33 被引用数 (Scopus)

抄録

A 62-year-old man was admitted to our emergency department owing to prolonged chest pain that had lasted for 3 h. An electrocardiogram showed ST elevation in leads I, aVL, and V1-6, and the patient’s laboratory revealed elevated myocardial necrosis marker levels. Emergency coronary angiography showed total occlusion of the proximal left anterior descending coronary artery. Subsequent percutaneous coronary intervention was performed by balloon angioplasty followed by stent implantation, and the patient showed improvement. However, echocardiographic examination 2 weeks after the percutaneous coronary intervention showed a thrombus (40 × 14 mm) in the apex of the left ventricle. In addition to dual antiplatelet therapy, apixaban was administered as anticoagulant therapy for the left ventricular thrombus. The size of the thrombus gradually decreased, and magnetic resonance imaging performed approximately 6 weeks after the initial apixaban administration showed no thrombus without a thromboembolic event. This case demonstrates that left ventricular thrombus can be resolved with apixaban treatment. Apixaban may be an effective alternative to vitamin K antagonist for some patients with acute myocardial infarction complicated by left ventricular thrombus.

本文言語English
ページ(範囲)118-123
ページ数6
ジャーナルHeart and vessels
31
1
DOI
出版ステータスPublished - 2016 1月 1
外部発表はい

ASJC Scopus subject areas

  • 循環器および心血管医学

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