Successful Surgical Treatment Combined With Infliximab in a Patient With Acute Aortic Regurgitation Caused by Behçet Disease

Yumiko Kawakubo, Yoshinori Katsumata, Jin Komuro, Yasuyuki Shiraishi, Shinsuke Yuasa, Yuji Itabashi, Takashi Kono, Keiichi Fukuda

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Standard aortic valve replacement for aortic regurgitation caused by Behçet disease (BD) is frequently complicated by postoperative recurrent prosthetic valve detachment. Tumour necrosis factor (TNF) α is known to be associated with higher inflammation activities. Therefore, the concomitant use of immunomodulatory agents with TNFα inhibitors may be the key to a better outcome. This is a case report of a 46-year-old woman with severe acute aortic regurgitation due to BD. Immunosuppressive therapy including the TNFα inhibitor infliximab, which has not been reported for perioperative use to date, resulted in the prompt remission of inflammation, leading to the success of Bentall surgery.

本文言語English
ページ(範囲)1161.e3-1161.e5
ジャーナルCanadian Journal of Cardiology
36
7
DOI
出版ステータスPublished - 2020 7月

ASJC Scopus subject areas

  • 循環器および心血管医学

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