Suppressors of cytokine signaling and immunity

Masato Kubo, Toshikatu Hanada, Akihiko Yoshimura

研究成果: Review article査読

512 被引用数 (Scopus)

抄録

The suppressors of cytokine signaling (SOCS) and cytokine-inducible SH2 protein are key physiological regulators of the immune system. Principally, SOCS1 and SOCS3 regulate T cells as well as antigen-presenting cells, including macrophages and dendritic cells. Here we review the function of SOCS1 and SOCS3 in innate and adaptive immunity, with particular emphasis on the relationship between immune regulation and SOCS.

本文言語English
ページ(範囲)1169-1176
ページ数8
ジャーナルNature Immunology
4
12
DOI
出版ステータスPublished - 2003 12
外部発表はい

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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