Surgical outcomes of laparoscopic versus open repeat liver resection for liver cancers: A report from a nationwide surgical database in Japan

Masaki Kaibori, Nao Ichihara, Hiroaki Miyata, Yoshihiro Kakeji, Atsushi Nanashima, Yuko Kitagawa, Hiroki Yamaue, Masakazu Yamamoto, Itaru Endo

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Background/Purpose: Laparoscopic (repeat) liver resection (LRLR) is a well-established liver tumor treatment. However, since its outcomes and comparison with open repeat liver resection (ORLR) in recurrent liver cancer remain inadequately studied, this study then aimed to compare their short-term outcomes for liver cancers (hepatocellular carcinoma, intrahepatic cholangiocellular carcinoma, and metastatic liver cancer). Methods: Repeat liver resection cases between 2013 and 2017 from Japan’s National Clinical Database were extracted. We used propensity score matching (PSM) to compare the proportion of patients with postoperative complications of Clavien-Dindo classification grade II or higher (CD2+) (primary endpoint), as well as the operative time, intraoperative bleeding volume, and intraoperative transfusion implementation rate (secondary endpoints). Results: Of 2902 patients (ORLR, 2476; LRLR, 426), 712 (356 per type) with comparable backgrounds remained via PSM. Before and after PSM, the postoperative CD2+ complication rate was significantly lower in the LRLR group, who had shorter operative time, smaller intraoperative bleeding volume, and lower intraoperative transfusion rate, than in the ORLR group (after matching, 7.6% vs 18.3%, P < 0.0001). Conclusions: LRLR showed better short-term outcomes than ORLR, making it a safer and more effective liver cancer treatment.

本文言語English
ページ(範囲)833-842
ページ数10
ジャーナルJournal of Hepato-Biliary-Pancreatic Sciences
29
8
DOI
出版ステータスPublished - 2022 8月
外部発表はい

ASJC Scopus subject areas

  • 外科
  • 肝臓学

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