Symptom generation

Juntaro Matsuzaki, Hidekazu Suzuki

研究成果: Chapter

抜粋

Patients whose dyspepsia symptoms had disappeared after 12 months from Helicobacter pylori (H. pylori) eradication therapy were decided to be called H. pylori-associated dyspepsia (HpD), and were clearly distinguished from functional dyspepsia. H. pylori eradication is more effective than placebo with a number needed to treat (NNT) of 14 for H. pylori-positive dyspepsia. H. pylori is likely to be associated with the presence of postprandial distress symptoms rather than epigastric pain symptoms, although the evidence whether therapeutic responses to H. pylori eradication differ between subgroups of dyspepsia is still limited. The altered ghrelin secretion from the stomach, the presence or severity of microscopic duodenitis, and altered expression of muscle-specific microRNAs in the gastric smooth muscle layer would be possible mechanisms of HpD.

元の言語English
ホスト出版物のタイトルHelicobacter Pylori
出版者Springer Japan
ページ125-130
ページ数6
ISBN(電子版)9784431557050
ISBN(印刷物)9784431557043
DOI
出版物ステータスPublished - 2016 1 1

    フィンガープリント

ASJC Scopus subject areas

  • Medicine(all)

これを引用

Matsuzaki, J., & Suzuki, H. (2016). Symptom generation. : Helicobacter Pylori (pp. 125-130). Springer Japan. https://doi.org/10.1007/978-4-431-55705-0_7