Syntheses of 1,5-dideoxy-1,5-imino-D-mannitol from D-mannose and from D-glucose

G. W.J. Fleet, M. J. Gough, T. K.M. Shing

研究成果: Article査読

42 被引用数 (Scopus)

抄録

Unambiguous enantiospecific syntheses of 1,5-dideoxy-1,5-imino-D-mannitol (LU1, 1-deoxy-mannojirimycin) are reported (i) from D-mannose via hydrogenation of a 5-azido-5-deoxy mannose, and (ii) from D-glucose, in which the key step involves nucleophilic substitution of a trifluoromethanesulphonyl group from C-2 of D-glucose.

本文言語English
ページ(範囲)4029-4032
ページ数4
ジャーナルTetrahedron Letters
25
36
DOI
出版ステータスPublished - 1984

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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