抄録
A novel nonnatural amino acid that carries a 2-anthraquinonyl group, L-2-anthraquinonylalanine, was first synthesized and converted to the corresponding N-carboxyanhydride (NCA). The NCA was polymerized to give poly(L-2-anthraquinonylalanine) in the form of a diblock copolymer with poly(ethylene glycol) that is linked to the C-terminal. A triblock copolymer was also prepared with poly(γ-benzyl L-glutamate)s that are attached to both N- and C-terminals. CD spectra of the diblock copolymer showed a helical conformation that is different from a right-handed α-helix. Conformational analysis and theoretical CD calculation suggested that the poly(anthraquinonylalanine) unit prefers a left-handed α-helix with the lowest energy side-chain orientation.
本文言語 | English |
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ページ(範囲) | 2651-2656 |
ページ数 | 6 |
ジャーナル | Macromolecules |
巻 | 30 |
号 | 9 |
DOI | |
出版ステータス | Published - 1997 5月 5 |
外部発表 | はい |
ASJC Scopus subject areas
- 有機化学
- ポリマーおよびプラスチック
- 無機化学
- 材料化学