Synthesis of a novel glycosphingolipid from the millipede, Parafontaria laminata armigera, and the assembly of its carbohydrate moiety into multivalent structures

Noriyasu Hada, Yoshiko Sonoda, Tadahiro Takeda

研究成果: Article査読

19 被引用数 (Scopus)

抄録

A novel glycosphingolipid, β-d-Manp-(1→4)-[α-l-Fucp-(1→3)]-β-d-Glcp-(1→1)-Cer, found in the millipede, Parafontaria laminata armigera, and multivalent derivatives of its carbohydrate moiety were synthesized. As the key step, the target glycolipid (1) was obtained through an inversion reaction at the 2-position of a β-glucopyranoside residue yielding a β-mannopyranoside. In addition, the synthesis of fluorescently labeled trimer and tetramer glycoconjugates (2, 3) was achieved by iterative amide bond formation using a monomer unit (24).

本文言語English
ページ(範囲)1341-1352
ページ数12
ジャーナルCarbohydrate Research
341
10
DOI
出版ステータスPublished - 2006 7 24

ASJC Scopus subject areas

  • 分析化学
  • 生化学
  • 有機化学

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