Synthesis of crosslinked peptidoglycan fragments for investigation of their immunobiological functions

Yukari Fujimoto, Yasuko Konishi, Osamu Kubo, Mizuho Hasegawa, Naohiro Inohara, Koichi Fukase

研究成果: Article査読

18 被引用数 (Scopus)

抄録

The synthesis of crosslinked peptidoglycan (PGN) fragments from Streptococcus pneumoniae cell wall was achieved. The immunostimulatory activities, including the induction of IL-6 and the stimulation of the intracellular receptor Nod2, were also determined. The crosslinked PGN fragments were not major human Nod2 ligands.

本文言語English
ページ(範囲)3631-3634
ページ数4
ジャーナルTetrahedron Letters
50
26
DOI
出版ステータスPublished - 2009 7月 1
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 創薬
  • 有機化学

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