Synthesis of diazatricyclic common structure of madangamine alkaloids

Yuta Yanagita, Takahiro Suto, Naoya Matsuo, Yasuhiro Kurosu, Takaaki Sato, Noritaka Chida

研究成果: Article査読

18 被引用数 (Scopus)

抄録

A general synthetic route toward a diazatricyclic core common to the madangamine family is described. Ring-closing metathesis and palladium-catalyzed cycloisomerization provided the cis-fused diazadecalin structure, accompanied by formation of the N-Boc-enamine, which was utilized as an N-acyliminium ion equivalent. Direct cyclization from the N-Boc-enamine was achieved through the in situ formation of an N,O-acetal.

本文言語English
ページ(範囲)1946-1949
ページ数4
ジャーナルOrganic Letters
17
8
DOI
出版ステータスPublished - 2015 4月 17

ASJC Scopus subject areas

  • 生化学
  • 物理化学および理論化学
  • 有機化学

フィンガープリント

「Synthesis of diazatricyclic common structure of madangamine alkaloids」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル