Synthesis of new peptidic glycoclusters derived from β-alanine

Koji Sato, Noriyasu Hada, Tadahiro Takeda

研究成果: Article査読

18 被引用数 (Scopus)

抄録

The synthesis of an asymmetric glycocluster 1 has been achieved by coupling of a sugar unit with the β-alanine polypeptide, the principal chain, and combining a carbohydrate chain with the side chain causing it to branch from the N terminal. The synthesis of this side chain multivalent ligands is based on the scaffolding of some ω-amino acid (glycine, β-alanine, and GABA) derivatives. This method facilitated the synthesis of the cluster, of which the length of each unit differs.

本文言語English
ページ(範囲)9331-9335
ページ数5
ジャーナルTetrahedron Letters
44
52
DOI
出版ステータスPublished - 2003 12 22

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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