TY - JOUR
T1 - Synthesis of ribofuranosyl glycosides of echiguanines A and B, inhibitors of phosphatidylinositol 4-kinase
AU - Sanpei, Kasumi
AU - Saito, Yoshio
AU - Imoto, Masaya
AU - Umezawa, Kazuo
AU - Kato, Kuniki
PY - 1996/11/5
Y1 - 1996/11/5
N2 - The synthesis of ribofuranosyl glycosides of echiguanines A and B, PI 4-kinase inhibitors, was achieved from 2-amino-4-chloropyrrolo[2,3-d]pyrimidine and 2,3-O-isopropylidene-5-O-(t-butyl) dimethylsilyl-α-D-ribofuranosyl chloride. The ribofuranosyl echiguanine A weakly inhibited PI 4-kinase.
AB - The synthesis of ribofuranosyl glycosides of echiguanines A and B, PI 4-kinase inhibitors, was achieved from 2-amino-4-chloropyrrolo[2,3-d]pyrimidine and 2,3-O-isopropylidene-5-O-(t-butyl) dimethylsilyl-α-D-ribofuranosyl chloride. The ribofuranosyl echiguanine A weakly inhibited PI 4-kinase.
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U2 - 10.1016/0960-894X(96)00459-3
DO - 10.1016/0960-894X(96)00459-3
M3 - Article
AN - SCOPUS:0030571291
SN - 0960-894X
VL - 6
SP - 2487
EP - 2490
JO - Bioorganic and Medicinal Chemistry Letters
JF - Bioorganic and Medicinal Chemistry Letters
IS - 21
ER -