@article{5a147211397c47a6a324832a7f6bd1cc,
title = "Synthesis of verbenachalcone congeners and their biological assessment against activation of the NGF-mediated neurite outgrowth of PC12D cells' activity",
abstract = "Synthesis of the verbenachalcone derivatives 3-5 involving littorachalcone 2 from diaryl ether 7 enabled an SAR study of enhancement activity against the NGF-mediated neurite outgrowth from PC12D cells. Littorachalcone 2 and o-deoxyverbenachalcone 5 showed similar activity to that of verbenachalcone 1.",
keywords = "Anodic oxidation, Littorachalcone, NGF-mediated neurite outgrowth, Verbena littoralis, Verbenachalcone",
author = "Takamasa Tanabe and Takahisa Ogamino and Yoshifumi Shimizu and Masaya Imoto and Shigeru Nishiyama",
note = "Funding Information: This work was supported by a Grant-in-Aid for the 21st Century COE program {\textquoteleft}Keio Life Conjugated Chemistry{\textquoteright}, as well as Scientific Research C from the Ministry of Education, Culture, Sports, Science and Technology, Japan. The authors were indebted to Mr. Y. Shimizu of their Faculty for his technical assistance.",
year = "2006",
month = apr,
day = "15",
doi = "10.1016/j.bmc.2005.11.055",
language = "English",
volume = "14",
pages = "2753--2762",
journal = "Bioorganic and Medicinal Chemistry",
issn = "0968-0896",
publisher = "Elsevier Limited",
number = "8",
}