Synthetic bioluminescent coelenterazine derivatives

Ryo Nishihara, Daniel Citterio, Koji Suzuki

研究成果: Chapter

抄録

The development of coelenterazine (CTZ) derivatives resulting in superior optical characteristics is an efficient method to extend the range of its possible applications. Here, we describe the synthesis of three C-6 substituted CTZ derivatives retaining the recognition by Renilla luciferase (RLuc) and its derivatives. The novel derivatives are useful as bright blue-shifted CTZ derivatives, which can be used as an alternative to hitherto reported compound DeepBlueC™.

本文言語English
ホスト出版物のタイトルMethods in Molecular Biology
出版社Humana Press Inc.
ページ19-31
ページ数13
DOI
出版ステータスPublished - 2016

出版物シリーズ

名前Methods in Molecular Biology
1461
ISSN(印刷版)1064-3745

ASJC Scopus subject areas

  • 分子生物学
  • 遺伝学

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