Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of neogala-series glycolipid analogues containing a mannose residue from the earthworm Pheretima hilgendorfi

Noriyasu Hada, Akiko Matsusaki, Mutsumi Sugita, Tadahiro Takeda

研究成果: Article査読

13 被引用数 (Scopus)

抄録

Two kinds of glycosphingolipid analogues from the earthworm Pheretima hilgendorfi were synthesized as follows: the trisaccharide 2- (tetradecyl)hexadecyl α-D-mannopyranosyl-(1→4)-β-D-galactopyranosyl- (1→6)-β-D-galactopyranoside (13) and the tetrasaccharide 2-(tetradecyl) hexadecyl α-D-galactopyranosyl-(1→6)-[α-D-mannopyranosyl-(1→4)]-β-D- galactopyranosyl-(1→6)-β-D-galactopyranoside (20) were synthesized by stepwise condensation of suitably protected monosaccharide units. A 2- (trimethylsilyl)ethyl 2,3,4-tri-O-benzoyl-β-D-galactopyranoside derivative (5) was used as the glycosyl acceptor and thiophenyl derivatives of D- galactose and D-mannose were used as donors respectively.

本文言語English
ページ(範囲)1265-1268
ページ数4
ジャーナルChemical and Pharmaceutical Bulletin
47
9
DOI
出版ステータスPublished - 1999 9

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

フィンガープリント 「Synthetic studies on glycosphingolipids from protostomia phyla: Synthesis of neogala-series glycolipid analogues containing a mannose residue from the earthworm Pheretima hilgendorfi」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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