Synthetic studies on thiostrepton family of peptide antibiotics: Synthesis of the dihydroquinoline portion of thiostrepton, the siomycins, and the thiopeptins

Tomonori Mori, Yukiko Satouchi, Hiraku Tohmiya, Shuhei Higashibayashi, Kimiko Hashimoto, Masaya Nakata

研究成果: Article

12 引用 (Scopus)

抜粋

Synthesis of the dihydroquinoline portion of thiostrepton, the siomycins, and the thiopeptins, members of the thiostrepton family of peptide antibiotics, has been achieved featuring the one-pot olefination via the Matsumura- Boekelheide rearrangement "using trifluoromethanesulfonic anhydride and triethylamine" and the stereoselective addition reaction controlled by the stereocenter of the peri-position.

元の言語English
ページ(範囲)6417-6422
ページ数6
ジャーナルTetrahedron Letters
46
発行部数38
DOI
出版物ステータスPublished - 2005 9 19

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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