Thalamic reticular nucleus in the thalamocortical loop

研究成果: Review article査読

8 被引用数 (Scopus)

抄録

Dynamic binding of different brain areas is critical for various cognitive functions. The thalamic reticular nucleus (TRN) is a GABAergic nucleus that constrains information flow through thalamocortical loop by providing inhibitory innervation to the thalamus. In this review, I summarize anatomical and single-cell-level physiological studies of the rodent TRN. Diversity and heterogeneity of TRN neurons in terms of axonal innervation, molecular expression, and physiological characteristics are described. I also outline thalamocortical and cortico-cortical connections with emphasis on interaction with the TRN. In summary, it is proposed that functional connectivity among brain regions are modulated with gating of transthalamic information flow by the TRN.

本文言語English
ページ(範囲)32-40
ページ数9
ジャーナルNeuroscience Research
156
DOI
出版ステータスPublished - 2020 7月

ASJC Scopus subject areas

  • 神経科学(全般)

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