The basic and clinical studies on cefsulodin in pediatric field

Hironobu Akita, Satoshi Iwata, Yukio Iwasaki, Takefumi Kanemitsu, Haruki Hattori, Keiji Jozaki, Masahiro Hotta, Naoya Yamashita, Seiichiro Nanri, Keisuke Sunagawa, Takashi Iwata, Mitsuru Osano, Yasuo Ichihashi

研究成果: Article査読

抄録

A new cephalosporin cefsulodin (CFS) was studied basically and clinically and the following results were obtained. 1. The serum levels of 25 mg/kg of CFS administered intravenously were 39.5 mcg/ml after 30 minutes, 22.6mcg/ml after1hour, 11.6 mcg/ml after 2 hours, 6.0 mcg/ml after 4 hours and 2.1 mcg/ml after 6 hours. The half life from serum was 84 minutes. 2. Clinical response on 4 cases of Pseudomonas aeruginosa infections were all good. 3. The slight elevations of GOT,GPT were observed by the drug administrations in1case. From the above results, CFS was effective drug to P. aeruginosa infections by intravenous administration of 25 mg/kg of CFS.

本文言語English
ページ(範囲)2652-2656
ページ数5
ジャーナルthe japanese journal of antibiotics
35
11
DOI
出版ステータスPublished - 1982 1 1

ASJC Scopus subject areas

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

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