The common marmoset as a novel animal model system for biomedical and neuroscience research applications

Hideyuki Okano, Keigo Hikishima, Atsushi Iriki, Erika Sasaki

研究成果: Review article査読

127 被引用数 (Scopus)

抄録

The common marmoset (Callithrix jacchus), a small New World primate, has been attracting much attention in the research field of biomedical science and neuroscience, based on its (i) cross-reactivity with human cytokines or hormones, (ii) comparative ease in handling due to its small size, (iii) high reproductive efficiency, (iv) establishment of basic research tools, and (v) advantages of its unique behavioral and cognitive characters. Various neurological disease models have been developed in the common marmoset, including Parkinson's disease, Huntington's disease, Alzheimer's disease, stroke, multiple sclerosis and spinal cord injury. We recently developed transgenic common marmoset with germline transmission, which is expected to provide a new animal model for the study of human diseases. In this review, we summarize the recent progress of biomedical research and neuroscience using common marmoset as an excellent model system.

本文言語English
ページ(範囲)336-340
ページ数5
ジャーナルSeminars in Fetal and Neonatal Medicine
17
6
DOI
出版ステータスPublished - 2012 12

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

フィンガープリント 「The common marmoset as a novel animal model system for biomedical and neuroscience research applications」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル