The effects of flow on the transport of potassium ions through the walls of single perfused frog mesenteric capillaries

M. Kajimura, S. D. Head, C. C. Michel

研究成果: Article査読

21 被引用数 (Scopus)

抄録

1. We have investigated the effects of varying flow velocity upon permeability to potassium ions (P(K)) of single perfused mesenteric microvessels in pithed frogs. 2. P(K) was estimated using a development of the single bolus microperfusion technique at chosen flow velocities (U) in the range of 150-7000 μm s-1. 3. In thirty-seven out of forty-three vessels, there was a strong positive correlation between P(K) and U. Average values (median) for P(K)(μm s-1) were related to U (μm s-1) by the expression: P(K) = 0.0043U + 4.05 (n = 43). 4. The correlation between P(K) and U was independent of microvascular pressure (and hence fluid filtration) over the range of 5-70 cmH2O. 5. The correlation between P(K) and U was independent of the potassium concentration in the bolus over the range of 2-40 mmol l-1 and of the direction of the potassium flux through the capillary walls.

本文言語English
ページ(範囲)707-718
ページ数12
ジャーナルJournal of Physiology
511
3
DOI
出版ステータスPublished - 1998 9 15

ASJC Scopus subject areas

  • Physiology

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