The evaluation of postoperative bowel dysfunction in Japanese patients with rectal cancer

Yuki Kiyozumi, Toshiya Nagasaki, Shimpei Matsui, Toshiki Mukai, Yukiharu Hiyoshi, Tomohiro Yamaguchi, Takashi Akiyoshi, Yosuke Fukunaga

研究成果: Article査読

抄録

Purpose: The present study assessed postoperative bowel dysfunction in Japanese patients with rectal cancer, including patients who underwent preoperative radiotherapy (RT). Methods: A total of 277 rectal cancer patients who underwent primary resection were included in the analyses. A questionnaire survey was administered using the low anterior resection syndrome (LARS) score and Wexner score. Scores were determined one year after rectal surgery or diverting ileostomy closure. The LARS score was categorized as minor LARS (21–29) and major LARS (30–42). Results: The proportions of patients with minor and major LARS were significantly larger and Wexner scores significantly higher in patients with distal tumors and a lower anastomosis level than in those with proximal tumors and a higher anastomosis level. Among the patients with lower rectal cancer, the proportions with minor and major LARS were similar between those with and without preoperative RT. The Wexner scores in patients with preoperative RT were significantly higher than in patients without RT. A distal tumor location and lower anastomosis level were independent risk factors of major LARS in multivariate analyses. Conclusion: A distal tumor location, low anastomosis level, and preoperative RT might be associated with postoperative bowel dysfunction in rectal cancer patients.

本文言語English
ジャーナルSurgery today
DOI
出版ステータスAccepted/In press - 2022

ASJC Scopus subject areas

  • 外科

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