The expression of granulysin in systemic anaplastic large cell lymphoma in childhood

Noriko Kitamura, Yohko U. Katagiri, Mitsuko Itagaki, Yoshitaka Miyagawa, Keiko Onda, Hajime Okita, Akio Mori, Junichiro Fujimoto, Nobutaka Kiyokawa

研究成果: Article

12 引用 (Scopus)

抜粋

The expression of granulysin, a cytolytic protein produced by activated T and NK cells, has been revealed to be correlated with the prognosis of some adult cancer patients. By examination on various childhood lymphoma tissues, we found that granulysin level was especially high in systemic anaplastic large cell lymphoma (ALCL) cases, whereas no close correlation with the expression of CD96, a marker for activated T and NK cells, was observed. We further demonstrated that both ALCL cells in biopsy specimens and cell lines established from ALCL express granulysin, indicating some correlation of granulysin with biological features of ALCL.

元の言語English
ページ(範囲)908-912
ページ数5
ジャーナルLeukemia Research
33
発行部数7
DOI
出版物ステータスPublished - 2009 7 1
外部発表Yes

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

フィンガープリント The expression of granulysin in systemic anaplastic large cell lymphoma in childhood' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Kitamura, N., Katagiri, Y. U., Itagaki, M., Miyagawa, Y., Onda, K., Okita, H., Mori, A., Fujimoto, J., & Kiyokawa, N. (2009). The expression of granulysin in systemic anaplastic large cell lymphoma in childhood. Leukemia Research, 33(7), 908-912. https://doi.org/10.1016/j.leukres.2009.01.032