The function of the Drosophila argos gene product in the development of embryonic chordotonal organs

Masataka Okabe, Kazunobu Sawamoto, Hideyuki Okano

研究成果: Article査読

17 被引用数 (Scopus)

抄録

We characterized the embryonic expression pattern and mutant phenotypes of the Drosophila gene argos, which encodes a secreted protein with an epidermal growth factor motif. The argos null mutation caused an increase in chordotonal (Ch) organs in both the thoracic and the abdominal segments, whereas overexpression of the argos gene resulted in a decrease in these organs. We showed that the argos transcripts are expressed transiently in the cells surrounding the Ch organ precursor and that the gene rhomboid (rho), which is involved in the regulation of the number of Ch organs, acts epistatically to argos in this event. Our findings suggest that argos plays a role in Ch organ precursor formation and regulates the final number of Ch organs.

本文言語English
ページ(範囲)37-49
ページ数13
ジャーナルDevelopmental Biology
175
1
DOI
出版ステータスPublished - 1996 4 10
外部発表はい

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology
  • Cell Biology

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