The isolation and structures of euphoscopins a and b

Shosuke Yamamura; Seiji Kosemura; Shigeru Ohba; Masatoki Ito; Yoshihiko Saito

doi:10.1016/S0040-4039(01)92490-6

The isolation and structures of euphoscopins a and b

Shosuke Yamamura, Seiji Kosemura, Shigeru Ohba, Masatoki Ito, Yoshihiko Saito

研究成果: Article › 査読

39 被引用数 (Scopus)

抄録

Two new toxic substances, euphoscopins A and B, have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the p-bromobenzoate readily obtained on treatment of euphoscopin A with p-bromobenzoyl chloride - pyridine. These antitumor substances belong to a group of jatrophone-type diterpenes.

本文言語	English
ページ（範囲）	5315-5318
ページ数	4
ジャーナル	Tetrahedron Letters
巻	22
号	52
DOI	https://doi.org/10.1016/S0040-4039(01)92490-6
出版ステータス	Published - 1981

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/S0040-4039(01)92490-6

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AU - Ohba, Shigeru

AU - Ito, Masatoki

AU - Saito, Yoshihiko

PY - 1981

Y1 - 1981

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AB - Two new toxic substances, euphoscopins A and B, have been isolated from the plant Euphorbia helioscopia L., and their absolute stereostructures also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the p-bromobenzoate readily obtained on treatment of euphoscopin A with p-bromobenzoyl chloride - pyridine. These antitumor substances belong to a group of jatrophone-type diterpenes.

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

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The isolation and structures of euphoscopins a and b

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