The Major Pectic Arabinogalactan Having Activity on the Reticuloendothelial System from the Roots and Rhizomes of Saposhnikovia divaricata

Noriko Shimizu, Masashi Tomoda, Ryoko Gonda, Mieko Kanari, Noriko Takanashi, Nahoko Takahashi

研究成果: Article査読

65 被引用数 (Scopus)

抄録

The major acidic polysaccharide, named saposhnikovan A, was isolated from the roots and rhizomes of Saposhnikovia divaricata. It showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test. It is composed of L-arabinose: d-galactose: D-galacturonic acid in the molar ratio of 6:15:10, and its molecular weight was estimated to be 54000. About 35 % of the D-galacturonic acid residues exist as the methyl esters. Methylation analysis, 13C-nuclear magnetic resonance, and controlled Smith degradation studies indicated that the polysac-charide has the α-l→4-linked D-galacturonan backbone bearing α-l→5-linked L-arabino-β-3,6-branched D-galactan side chains.

本文言語English
ページ(範囲)1329-1332
ページ数4
ジャーナルChemical and Pharmaceutical Bulletin
37
5
DOI
出版ステータスPublished - 1989

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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