The microbiome in infectious disease and inflammation

Kenya Honda, Dan R. Littman

研究成果: Review article

419 被引用数 (Scopus)

抄録

The mammalian alimentary tract harbors hundreds of species of commensal microorganisms (microbiota) that intimately interact with the host and provide it with genetic, metabolic, and immunological attributes. Recent reports have indicated that the microbiota composition and its collective genomes (microbiome) are major factors in predetermining the type and robustness of mucosal immune responses. In this review, we discuss the recent advances in our understanding of host-microbiota interactions and their effect on the health and disease susceptibility of the host.

本文言語English
ページ(範囲)759-795
ページ数37
ジャーナルAnnual Review of Immunology
30
DOI
出版ステータスPublished - 2012 4

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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