The new pemphigus variants

N. D. Robinson, T. Hashimoto, M. Amagai, L. S. Chan

研究成果: Article査読

214 被引用数 (Scopus)

抄録

Pemphigus describes a group of autoimmune diseases characterized by blisters and erosions of the skin and mucous membranes, acantholysis by histology, and autoantibodies directed against epidermal cell surface components. Since the early 1970s, the following new clinical variants of pemphigus have been reported: pemphigus herpetiformis, IgA pemphigus, and paraneoplastic pemphigus. In recent years, significant data have been obtained from laboratory investigation on these rare and atypical variants, especially regarding their specific target antigens. We review these variants, their clinical presentations, histologic findings, immunopathology, target antigens, theories of pathogenesis, treatment modalities, and clinical courses.

本文言語English
ページ(範囲)649-671
ページ数23
ジャーナルJournal of the American Academy of Dermatology
40
5 I
DOI
出版ステータスPublished - 1999
外部発表はい

ASJC Scopus subject areas

  • 皮膚病学

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