The successful prevention of thromboembolism using rivaroxaban in a patient with antithrombin deficiency during the perioperative period

Hidetsugu Kawai, Hiromichi Matsushita, Hiroshi Kawada, Yoshiaki Ogawa, Kiyoshi Ando

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Antithrombin (AT) deficiency, a rare disorder of the coagulation system, is a serious risk factor for thromboembolism. Approximately 50-90% of patients with AT deficiency develop thromboembolism during their lifetime. In addition, surgery is a major risk factor for thromboembolism in these patients. We herein report the case of a 90-year-old woman with AT deficiency who was safely and successfully managed using rivaroxaban (a direct oral factor Xa inhibitor) during the perioperative period of surgery for right femur fracture. The present case illustrates the effectiveness of rivaroxaban in preventing thromboembolisms due to surgery, even in very elderly patients with antithrombin deficiency. Further investigations are needed to determine the optimal dosage of rivaroxaban.

本文言語English
ページ(範囲)2339-2342
ページ数4
ジャーナルInternal Medicine
56
17
DOI
出版ステータスPublished - 2017
外部発表はい

ASJC Scopus subject areas

  • 内科学

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