Theoretical and experimental investigation of the influence of frontal sinus on the sensitivity of the NIRS Signal in the adult head

Eiji Okada, Daisuke Yamamoto, Naoya Kiryu, Akihisa Katagiri, Noriaki Yokose, Takashi Awano, Kouji Igarashi, Sin Nakamura, Tatsuya Hoshino, Yoshihiro Murata, Tsuneo Kano, Kaoru Sakatani, Yoichi Katayama

研究成果: Conference contribution

12 被引用数 (Scopus)

抄録

The sensitivity of the near-infrared spectroscopy signal to the brain activation depends on the thickness and structure of the superficial tissues. The influence of the frontal sinus, which is void region in the skull, on the sensitivity to the brain activation is investigated by the time-resolved experiments and the theoretical modelling of the light propagation in the head. In the time-resolved experiments, the mean-time of flight for the forehead scarcely depends upon the existence of the frontal sinus when probe spacing was shorter than 30 mm. The partial optical path length in the brain, which indicates the sensitivity of the near-infrared spectroscopy signal to the brain activation, in a simplified head model is predicted by Monte Carlo simulation. The influence of the frontal sinus on the sensitivity of the signal depends on the thickness of the skull and the depth of the frontal sinus.

本文言語English
ホスト出版物のタイトルOxygen Transport to Tissue XXXI
編集者Eiji Takahashi, Duane Bruley
ページ231-236
ページ数6
DOI
出版ステータスPublished - 2010

出版物シリーズ

名前Advances in Experimental Medicine and Biology
662
ISSN(印刷版)0065-2598

ASJC Scopus subject areas

  • 生化学、遺伝学、分子生物学(全般)

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