抜粋
Inflammatory bowel disease is thought to result from inappropriate activation of mucosal immune responses. Intestinal epithelial cells produce interleukin (IL)-7 that serves as a regulatory factor for IL-7 receptor (IL-7R)(+) mucosal lymphocytes. The pivotal role of mucosal IL-7/IL-7R dependent signals in the activation of mucosal immune responses that lead to the development of chronic intestinal inflammation are demonstrated. Therapeutic approaches targeting IL-7/IL-7R signal pathway may be feasible in the treatment of inflammatory bowel disease.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 119-123 |
| ページ数 | 5 |
| ジャーナル | Current drug targets. Inflammation and allergy |
| 巻 | 2 |
| 発行部数 | 2 |
| DOI | |
| 出版物ステータス | Published - 2003 6 |
| 外部発表 | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology
- Pharmacology
フィンガープリント Therapeutic approaches to chronic intestinal inflammation by specific targeting of mucosal IL-7/IL-7R signal pathway.' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。
これを引用
Watanabe, M., Yamazaki, M., Okamoto, R., Ohoka, S., Araki, A., Nakamura, T., & Kanai, T. (2003). Therapeutic approaches to chronic intestinal inflammation by specific targeting of mucosal IL-7/IL-7R signal pathway. Current drug targets. Inflammation and allergy, 2(2), 119-123. https://doi.org/10.2174/1568010033484269