Thermally responsive chromatographic materials using functional polymers

Hideko Kanazawa

研究成果: Review article査読

50 被引用数 (Scopus)

抄録

Functional polymers that respond to small changes in environmental stimuli with large changes in their structure and properties are often called "intelligent" polymers. We have modified material surfaces with such polymers and used them in separation systems. Silica beads were modified with the temperature-responsive polymer poly(N-isopropylacrylamide) (PNIPAAm). PNIPAAm-grafted surfaces exhibited temperature-driven alterations of hydrophilic-hydrophobic surface-properties. Using this feature, PNIPAAm and related temperature-responsive polymers have been used to generate temperature-sensitive stationary phases for chromatographic separations. We attached several different functional polymers, including temperature- and pH-responsive polymers, to silica beads. These temperature-responsive stationary phases are useful in development of separation methods since adjusting the temperature represents an extra tool for optimizing the selectivity. Applications of thermally responsive columns for separations in the HPLC mode are demonstrated.

本文言語English
ページ(範囲)1646-1656
ページ数11
ジャーナルJournal of Separation Science
30
11
DOI
出版ステータスPublished - 2007 7月 1

ASJC Scopus subject areas

  • 分析化学
  • ろ過および分離

フィンガープリント

「Thermally responsive chromatographic materials using functional polymers」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル