Thymoma-associated graft-versus-host disease-like erythroderma

Tomoyuki Nakagiri, Meinoshin Okumura, Masayoshi Inoue, Masato Minami, Eiji Kiyohara, Noriko Umegaki, Toshiaki Nakamura, Yasuhiko Tomita, Ichirou Katayama, Katsuyuki Aozasa

研究成果: Article査読

18 被引用数 (Scopus)


We report a 40-year-old woman with recurrent thymoma associated with myasthenia gravis, in whom an unusual form of erythroderma developed. A histological examination revealed a graft-versus-host disease (GVHD)-like reaction. After high-dose steroid therapy, the metastatic thymoma lesion in the abdominal cavity was reduced in size from 9.5 × 6 × 7.5 cm to 4 × 3 × 1 cm in diameter. Nevertheless, the GVHD-like erythroderma become aggravated, her condition worsened, and the patient finally suffered from respiratory failure and died of sepsis. A GVHD-like reaction may be a rare presentation of thymoma-associated immunological disorders such as myasthenia gravis or pure red cell aplasia. Herein, we discuss the present case and review pertinent reports of thymoma cases associated with GVHD.

ジャーナルJournal of Thoracic Oncology
出版ステータスPublished - 2007 12

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

フィンガープリント 「Thymoma-associated graft-versus-host disease-like erythroderma」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。