Toll-like receptor signaling and IRF transcription factors

Kenya Honda, Tadatsugu Taniguchi

研究成果: Article査読

47 被引用数 (Scopus)

抄録

Interferon regulatory factors (IRFs) were originally discovered in the context of type I interferon (IFN-α/β) gene induction, and subsequent studies on these transcription factors have revealed their remarkable functional diversity in regulating immune systems. Indeed, the critical involvement of IRF members in innate and adaptive immune responses has recently gained much attention, particularly with the recent discovery of Toll-like receptors (TLRs) and analyses of their critical functions in linking the innate and adaptive immune responses.

本文言語English
ページ(範囲)290-295
ページ数6
ジャーナルIUBMB Life
58
5-6
DOI
出版ステータスPublished - 2006 5月
外部発表はい

ASJC Scopus subject areas

  • 生化学
  • 分子生物学
  • 遺伝学
  • 臨床生化学
  • 細胞生物学

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