Total synthesis of homoerythrinan alkaloids, schelhammericine and 3-epischelhammericine

Yoshisuke Tsuda, Takeshi Ohshima, Shinzo Hosoi, Satomi Kaneuchi, Fumiyuki Kiuchi, Jun Toda, Takehiro Sano

研究成果: Article査読

20 被引用数 (Scopus)

抄録

Total syntheses of two homoerythrinan alkaloids, schelhammericine and 3-epischelhammericine, are described. Photocycloaddition of a dioxopyrrolobenzazepine to 1-methoxy-3-trimethylsilyloxybutadiene afforded, in a regio- and stereo-specific manner, the cyclobutane derivative, which was converted to a homoerythrinan derivative by utilizing a TBAF-induced 1,3-anionic rearrangement. The product was transformed into the title alkaloids in several steps.

本文言語English
ページ(範囲)500-508
ページ数9
ジャーナルChemical and Pharmaceutical Bulletin
44
3
DOI
出版ステータスPublished - 1996 3月
外部発表はい

ASJC Scopus subject areas

  • 化学 (全般)
  • 創薬

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