The first complete synthesis of antibiotic hygromycin A is reported; coupling of the protected sugar moiety (2) and the aminocyclitol (3) derived from D-glucose as the optically active from, followed by deprotection, gives the product (1) which was identified with an aunthentic sample by 400 MHz 1H n.m.r. spectroscopy.
|ジャーナル||Journal of the Chemical Society, Chemical Communications|
|出版ステータス||Published - 1989 1月 1|
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