Total synthesis of nucleoside antibiotics possessing novel N-glycoside structures

Noritaka Chida

研究成果: Article査読

9 被引用数 (Scopus)

抄録

Construction of aryl and heteroaryl N-glycoside structures by way of the palladium-catalyzed Buchwald-Hartwig N-arylation of pyranosylamines with aryl and heteroaryl halide derivatives is described. This methodology was successfully applied to the total synthesis of nucleoside antibiotics, spicamycin and dapiramicin B, possessing novel heteroaryl N-glycosides. Kinetic and thermodynamic analyses of heteroaryl N-glycosides are also reported.

本文言語English
ページ(範囲)1105-1115
ページ数11
ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
66
11
DOI
出版ステータスPublished - 2008 11月

ASJC Scopus subject areas

  • 有機化学

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