@article{61311714dd544ca4a6653a6e37b7494f,
title = "Total Synthesis of Paclitaxel",
abstract = "The total synthesis of paclitaxel (Taxol) is described. Double Rubottom oxidation of the bis(silyl enol ether) derived from a tricarbocyclic diketone effectively installed a bridgehead olefin and C-5/C-13 hydroxy groups in a one-step operation. The novel Ag-promoted oxetane formation smoothly constructed the tetracyclic framework of paclitaxel.",
author = "Shota Iiyama and Keisuke Fukaya and Yu Yamaguchi and Ami Watanabe and Hiroaki Yamamoto and Shota Mochizuki and Ryosuke Saio and Takashi Noguchi and Takeshi Oishi and Takaaki Sato and Noritaka Chida",
note = "Funding Information: This work was supported by a Grant-in Aid for Scientific Research (B) from JSPS (26288018). Publisher Copyright: {\textcopyright} 2021 American Chemical Society",
year = "2022",
month = jan,
day = "14",
doi = "10.1021/acs.orglett.1c03851",
language = "English",
volume = "24",
pages = "202--206",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "1",
}