Total synthesis of the trisaccharide of olivomycin A

Kazunobu Toshima, Yuko Nozaki, Masaya Nakata, Kuniaki Tatsuta, Mitsuhiro Kinoshita

研究成果: Article

9 引用 (Scopus)

抜粋

The total synthesis of the trisaccharide of olivomycin A, which is one of the aureolic acid antitumor antibiotics, has been achieved. Our approach involves highly stereocontrolled glycosidations using 2,6-ahnydro-2-thio glycosyl donors. The 2,6-anhydro-2-thio trisaccharide 21 was constructed from 4 and 5, and then converted into the 2,6-dideoxy trisaccharide of olivomycin A 3 by hydrogenolysis and deprotection.

元の言語English
ページ(範囲)5761-5764
ページ数4
ジャーナルTetrahedron Letters
34
発行部数36
DOI
出版物ステータスPublished - 1993 9 3

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

フィンガープリント Total synthesis of the trisaccharide of olivomycin A' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Toshima, K., Nozaki, Y., Nakata, M., Tatsuta, K., & Kinoshita, M. (1993). Total synthesis of the trisaccharide of olivomycin A. Tetrahedron Letters, 34(36), 5761-5764. https://doi.org/10.1016/S0040-4039(00)73854-8