New transcutaneous monitoring methods for biochemical substances such as blood glucose and lactate have been developed by using a suction effusion fluid (SEF) collecting technique with an ion-sensitive field-effect transistor for blood glucose, and with a micro-planar amperometric biosensor for lactate respectively. Firstly, blood glucose change during the 75-g oral glucose tolerance test (OGTT) was monitored by suction effusion fluid (SEF) sampling in five patients with type II diabetes. Secondly, we have also developed a micro-planar biosensor for determining lactate concentration in very small sample. The biosensor utilizes a lactate oxidase immobilizes membrane on a micro planar platinum electrode to yield a lactate sensor. Both glucose and lactate concentrations measured with SEF showed good correlation with those obtained directly from whole blood.
|ジャーナル||Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings|
|出版ステータス||Published - 1996 12月 1|
|イベント||Proceedings of the 1996 18th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Part 2 (of 5) - Amsterdam, Neth|
継続期間: 1996 10月 31 → 1996 11月 3
ASJC Scopus subject areas
- コンピュータ ビジョンおよびパターン認識